Monday, October 15, 2007

Class: October 15th 2007

Today we reviewed the paper about lambda phage. We derived all the modeling equations that lead to the behaviour of the cI/cro operon during lysogenic "life style". In addition we saw how the cannonical representation can be deduced from our previous knowledge and showed the repression curves of the PR and PRM promoters as a function of the total amount of repressor that is in the system. The calculation of these curves lies on the calculation of the Gibbs free energies and we saw that those energies can be computed by means of the wild-type and mutant experiments.
For those of you that are interested, in THIS link you will find a more detailed explanation about lambda phage (FLASH required).
Next day will be our last class for this block and we will see that non-equilibrium thermodynamics can be also very useful in biophysics....

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